Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797685 | 0.91 | HDAC1 (0.34) | LMNAHDAC6HDAC1MEN1KMT2A | |
| SCHEMBL8798099 | 0.87 | VCAM1 (0.34) | LMNAHDAC6HDAC1MEN1KMT2A | |
| SCHEMBL8798236 | 0.87 | MEN1 (0.36) | LMNATSHRHSD17B10HDAC6NPC1 | |
| SCHEMBL8798368 | 0.87 | SMN1; SMN2 (0.39) | LMNANPC1MAPK1KMT2AMTNR1A | |
| SCHEMBL8798797 | 0.74 | NPC1 (0.36) | NPC1HDAC1MEN1KMT2AMAPT | |
| SCHEMBL8799596 | 0.73 | VCAM1 (0.39) | LMNAHDAC6NPC1HDAC1MEN1 | |
| SCHEMBL8703601 | 0.73 | MAPK14 (0.47) | LMNAHSD17B10NPC1MAPK1MEN1 | |
| SCHEMBL8798554 | 0.72 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL8801653 | 0.71 | LPAR1 (0.34) | LMNAMEN1KMT2A | |
| SCHEMBL8798530 | 0.70 | SMN1; SMN2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790240-A1 | Phenol-derivatives having pharmaceutical activity and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1997-08-20 | — | — | EP | disclosed |