Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | FLT4 | P35916 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798826 | 0.89 | MAPT (0.37) | MAPTALDH1A1TP53GAAKMT2A | |
| SCHEMBL8798530 | 0.84 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL8798554 | 0.81 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL8798368 | 0.80 | SMN1; SMN2 (0.39) | ALDH1A1KMT2AMAPK1TDP1CNR1 | |
| SCHEMBL8804341 | 0.67 | LMNA (0.34) | MAPTTP53KMT2AMEN1MAPK1 | |
| SCHEMBL8702537 | 0.65 | RECQL (0.39) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL8707922 | 0.64 | CA1 (0.41) | ALDH1A1GAATDP1EGFR | |
| SCHEMBL8702761 | 0.64 | LPAR1 (0.39) | MAPTKMT2AMEN1NPSR1 | |
| SCHEMBL11626762 | 0.64 | ALDH1A1 (0.56) | ALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL8703601 | 0.63 | MAPK14 (0.47) | MAPTALDH1A1KMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790240-A1 | Phenol-derivatives having pharmaceutical activity and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1997-08-20 | — | — | EP | disclosed |