Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 3/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 2/20 | 0.41 |
| ▸ | PTPRB | P23467 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.40 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798271 | 0.91 | SLC2A1 (0.47) | SLC2A1EPHX2GPR119STSTGFBR1 | |
| Hydrochloric Acid SCHEMBL8798541 | 0.84 | ALDH1A1 (0.41) | EPHX2PKMALDH1A1 | |
| Hydrochloric Acid SCHEMBL8798247 | 0.76 | GAA (0.47) | KDM4EALDH1A1 | |
| SCHEMBL3082993 | 0.74 | KDM4E (0.53) | SLC2A1KDM4EPKMLIMK2YAP1 | |
| SCHEMBL8799906 | 0.74 | UBE2M (0.41) | — | |
| SCHEMBL19867107 | 0.73 | KDM4E (0.58) | KDM4EPKMLIMK2YAP1JAK2 | |
| SCHEMBL1622025 | 0.72 | JAK2 (0.60) | SLC2A1KDM4EPKMLIMK2JAK2 | |
| SCHEMBL1623986 | 0.72 | JAK2 (0.60) | SLC2A1KDM4EPKMLIMK2JAK2 | |
| SCHEMBL15462496 | 0.72 | JAK2 (0.60) | SLC2A1KDM4EPKMLIMK2JAK2 | |
| SCHEMBL8799426 | 0.69 | ACHE (0.42) | EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790240-A1 | Phenol-derivatives having pharmaceutical activity and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1997-08-20 | — | — | EP | disclosed |