Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL281995 | 0.92 | NPC1 (0.39) | ACHEPPARAPPARGPPARDNPC1 | |
| Hydrochloric Acid SCHEMBL6245752 | 0.91 | NPC1 (0.39) | ACHEPPARAPPARGPPARDNPC1 | |
| SCHEMBL3740322 | 0.90 | RAB9A (0.38) | ACHEPPARAPPARGPPARDNPC1 | |
| Hydrochloric Acid SCHEMBL9068017 | 0.84 | ACHE (0.38) | ACHEPPARAPPARGPPARDNPC1 | |
| SCHEMBL8799725 | 0.84 | ACHE (0.37) | ACHEPPARAPPARGPPARDNPC1 | |
| SCHEMBL8799596 | 0.82 | VCAM1 (0.39) | PPARAPPARGPPARDNPC1RAB9A | |
| SCHEMBL8798236 | 0.80 | MEN1 (0.36) | PPARAPPARGPPARDNPC1CA1 | |
| SCHEMBL8706854 | 0.79 | USP2 (0.46) | PPARAPPARGPPARDALDH1A1HPGD | |
| SCHEMBL8798797 | 0.79 | NPC1 (0.36) | ACHEPPARAPPARGPPARDNPC1 | |
| Hydrochloric Acid SCHEMBL8798777 | 0.77 | ACHE (0.39) | ACHEPPARACASRMMP3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790240-A1 | Phenol-derivatives having pharmaceutical activity and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1997-08-20 | — | — | EP | disclosed |
| EP-0355827-B1 | Hydantoin derivatives | MOCHIDA PHARM CO LTD (JP) | 1997-01-02 | — | — | EP | disclosed |
| WO-1990002126-A1 | HYDANTOIN DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-03-08 | — | — | WO | disclosed |