Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7891308 | 0.82 | NPSR1 (0.41) | NPSR1SMN1; SMN2KMT2ACYP3A4CYP2C19 | |
| SCHEMBL6933247 | 0.80 | KMT2A (0.47) | NPSR1SMN1; SMN2KMT2ACYP3A4CYP2C19 | |
| SCHEMBL5533132 | 0.78 | CES1 (0.43) | NPSR1SMN1; SMN2KMT2ACYP3A4CYP2C19 | |
| SCHEMBL6928667 | 0.76 | KMT2A (0.43) | NPSR1SMN1; SMN2KMT2ACYP3A4CYP2C19 | |
| SCHEMBL6933565 | 0.74 | ATM (0.41) | NPSR1SMN1; SMN2KMT2ACYP3A4CYP2C19 | |
| SCHEMBL3641338 | 0.74 | NPSR1 (0.46) | NPSR1SMN1; SMN2KMT2ACYP3A4CYP2C19 | |
| SCHEMBL11115139 | 0.73 | NPSR1 (0.56) | NPSR1SMN1; SMN2KMT2ACYP3A4CYP2C19 | |
| SCHEMBL3730131 | 0.73 | NPSR1 (0.50) | NPSR1SMN1; SMN2KMT2ACYP3A4CYP2C19 | |
| SCHEMBL6932838 | 0.73 | ALDH1A1 (0.43) | NPSR1SMN1; SMN2KMT2ACYP3A4CYP2C19 | |
| SCHEMBL5932378 | 0.72 | NPSR1 (0.48) | NPSR1SMN1; SMN2KMT2ACYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517476-B1 | Benzimidazole derivatives, a method for producing the same, agricultural and horticultural fungicides containing the same as an active ingredient and intermediate compounds thereof | SUMITOMO CHEMICAL CO (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-5472974-A | Benzimidazole derivatives, agricultural and horticultural fungicides containing the same as an active ingredient and intermediate compounds thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-12-05 | — | — | US | disclosed |
| US-5395952-A | Nonphytotoxic | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-03-07 | — | — | US | disclosed |
| US-5310747-A | Benzimidazole derivatives, agricultural and horticultural fungicides containing the same as an active ingredient and intermediate compounds thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5234938-A | BENZIMIDAZOLE DERIVATIVE, ITS INTERMEDIATE COMPOUNDS AND AN AGRICULTURAL AND HORTICULTURAL FUNGICIDE CONTAINING THE BENZIMIDAZOLE DERIVATIVE AS AN ACTIVE INGREDIENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0517476-A2 | Benzimidazole derivatives, a method for producing the same, agricultural and horticultural fungicides containing the same as an active ingredient and intermediate compounds thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1992-12-09 | — | — | EP | disclosed |
| EP-0487286-A1 | Benzimidazole derivative, a method for producing the same, its intermediate compounds and an agricultural and horticultural fungicide containing the benzimidazole derivative as an active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-05-27 | — | — | EP | disclosed |