Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549098 | 0.88 | RAB9A (0.41) | RAB9ANPC1PPARGNCOR2POLB | |
| SCHEMBL7556390 | 0.82 | NAPRT (0.37) | RAB9ANPC1POLBBTKNAPRT | |
| SCHEMBL8799100 | 0.78 | KDM4E (0.44) | RAB9ANPC1PPARGNCOR2POLB | |
| SCHEMBL8798744 | 0.77 | NAPRT (0.44) | RAB9ANAPRTKDM4EKDM4AKDM4C | |
| SCHEMBL7553608 | 0.76 | NAPRT (0.46) | NAPRTKDM4CKMT2A | |
| SCHEMBL8813141 | 0.74 | NAPRT (0.44) | RAB9ANPC1PPARGGSK3BNAPRT | |
| SCHEMBL7551656 | 0.74 | TDP1 (0.39) | RAB9ANPC1POLBNAPRTNAMPT | |
| SCHEMBL19857454 | 0.74 | NAPRT (0.57) | RAB9ANAPRTKDM4EKDM6BKDM4A | |
| SCHEMBL13720986 | 0.73 | ALOX15 (0.53) | PPARGNCOR2POLBPKMGSK3B | |
| SCHEMBL9059311 | 0.73 | NAPRT (0.34) | RAB9ANPC1NAPRTKDM4EKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |