Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | KDM4A | O75164 | 2/20 | 0.44 |
| ▸ | KDM5C | P41229 | 2/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546196 | 0.89 | KDM4E (0.38) | KDM4EKDM4AKDM5CKDM6BKDM4D | |
| SCHEMBL9059311 | 0.82 | NAPRT (0.34) | KDM4EKDM4AKDM5CKDM6BKDM4D | |
| SCHEMBL8798672 | 0.78 | RAB9A (0.42) | KDM4EKDM4AKDM5CKDM6BKDM4D | |
| SCHEMBL7547894 | 0.77 | MAPT (0.46) | KDM4EKDM4AKDM4CNAPRTKMT2A | |
| SCHEMBL7546681 | 0.76 | TDP1 (0.37) | KDM4ENAPRTPOLBKMT2APPARG | |
| SCHEMBL7556390 | 0.74 | NAPRT (0.37) | KDM4EKDM4AKDM5CKDM6BKDM4D | |
| SCHEMBL7546700 | 0.73 | ALOX5 (0.39) | KDM4EALOX5NAPRTPOLBKMT2A | |
| SCHEMBL7551790 | 0.73 | SGMS2 (0.36) | KDM4EKDM4CNAPRTPOLBASPH | |
| SCHEMBL7600813 | 0.72 | — | — | |
| SCHEMBL19857454 | 0.71 | NAPRT (0.57) | KDM4EKDM4AKDM6BKDM4DKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |