Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800118 | 0.94 | FKBP1A (0.37) | FKBP1AKMT2AMEN1ALDH1A1HTR2A | |
| SCHEMBL8798973 | 0.82 | FKBP1A (0.37) | FKBP1AEDNRBEDNRAKMT2AMEN1 | |
| SCHEMBL8803290 | 0.82 | LTA4H (0.46) | ALDH1A1 | |
| SCHEMBL8798966 | 0.79 | PTPRB (0.40) | FKBP1AKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL8798260 | 0.77 | LTA4H (0.38) | FKBP1AKMT2AMEN1 | |
| SCHEMBL8800124 | 0.77 | FKBP1A (0.36) | FKBP1AKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL8799063 | 0.76 | LTA4H (0.45) | LMNA | |
| SCHEMBL8331038 | 0.76 | CYP4F2 (0.33) | ALDH1A1 | |
| SCHEMBL8799950 | 0.75 | ALDH1A1 (0.38) | ALDH1A1KDM4EPOLB | |
| SCHEMBL8800131 | 0.75 | CYP4F2 (0.38) | KMT2AMEN1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |