Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803290 | 0.94 | LTA4H (0.46) | LTA4HSMN1; SMN2MMP1MMP3MMP9 | |
| SCHEMBL8329546 | 0.88 | LTA4H (0.52) | LTA4HLMNASMN1; SMN2MMP8 | |
| SCHEMBL8800118 | 0.83 | FKBP1A (0.37) | LMNA | |
| SCHEMBL8800131 | 0.82 | CYP4F2 (0.38) | LTA4HGRIK1CTSK | |
| SCHEMBL8798260 | 0.82 | LTA4H (0.38) | LTA4HSMN1; SMN2 | |
| SCHEMBL8799066 | 0.81 | LMNA (0.39) | LTA4HLMNAGRIK1SMN1; SMN2MMP1 | |
| SCHEMBL8633545 | 0.80 | SLC7A5 (0.43) | LTA4HLMNASMN1; SMN2MMP8 | |
| SCHEMBL15989154 | 0.80 | GRIK1 (0.55) | LTA4HLMNAGRIK1MMP1MMP3 | |
| SCHEMBL7077555 | 0.80 | GRIK1 (0.55) | LTA4HLMNAGRIK1MMP1MMP3 | |
| SCHEMBL8799950 | 0.79 | ALDH1A1 (0.38) | LTA4HSMN1; SMN2CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |