Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PTH1R | Q03431 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CCR6 | P51684 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL849854 | 0.82 | TSHR (0.54) | ARTAS2R8NPSR1POLBALDH1A1 | |
| SCHEMBL879679 | 0.79 | ALDH1A1 (0.53) | ARNPSR1ALDH1A1TSHRMAPT | |
| SCHEMBL850306 | 0.75 | TSHR (0.55) | ARNPSR1POLBALDH1A1TSHR | |
| SCHEMBL3841672 | 0.73 | AR (0.50) | ARALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL11633012 | 0.72 | AR (0.45) | ARTAS2R8NPSR1POLBALDH1A1 | |
| SCHEMBL11718007 | 0.72 | AR (0.45) | ARTAS2R8POLBGAAPHGDH | |
| SCHEMBL11722454 | 0.72 | AR (0.53) | ARTAS2R8POLBALDH1A1MAPT | |
| SCHEMBL8819678 | 0.72 | MAPT (0.58) | ARPOLBALDH1A1MAPTLMNA | |
| SCHEMBL849330 | 0.71 | AR (0.46) | ARNPSR1ALDH1A1TSHRMAPT | |
| SCHEMBL16302319 | 0.71 | GSK3A (0.54) | ALDH1A1TSHRSMN1; SMN2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-B9 | SPIROIMIDAZOLONE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2015-10-28 | — | — | EP | disclosed |