SCHEMBL849330

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL879679	0.81	ALDH1A1 (0.53)	ARNPC1RAB9APKMMAPT
	SCHEMBL850306	0.77	TSHR (0.55)	ARPKMMAPTKMT2AMEN1
	SCHEMBL28856178	0.74	MEN1 (0.50)	NPC1RAB9APKMMAPTKMT2A
	SCHEMBL11826970	0.74	PKM (0.59)	ARPKMMAPTKMT2AMEN1
	SCHEMBL16359018	0.72	AR (0.45)	ARPKMMAPTKMT2AMEN1
	SCHEMBL8819678	0.72	MAPT (0.58)	ARMAPTKMT2AMEN1ALDH1A1
	SCHEMBL10291202	0.71	AR (0.44)	ARPKMMAPTKMT2AMEN1
	SCHEMBL22472290	0.71	MEN1 (0.59)	NPC1RAB9APKMMAPTKMT2A
	SCHEMBL879903	0.71	AR (0.42)	ARNPC1RAB9APKMMAPT
	SCHEMBL849854	0.71	TSHR (0.54)	ARNPC1RAB9AMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.