SCHEMBL850306

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL879679	0.85	ALDH1A1 (0.53)	TSHRARGAAKMT2AALDH1A1
	SCHEMBL849854	0.81	TSHR (0.54)	TSHRARPOLBL3MBTL1GAA
	SCHEMBL11826970	0.77	PKM (0.59)	ARPOLBL3MBTL1GAAKMT2A
	SCHEMBL849330	0.77	AR (0.46)	TSHRARL3MBTL1GAAKMT2A
	SCHEMBL849686	0.77	AR (0.72)	ARALKBH5KMT2AMAPTNPSR1
	SCHEMBL16359018	0.76	AR (0.45)	TSHRARPOLBL3MBTL1GAA
	SCHEMBL5302868	0.75	FAAH (0.50)	ARPOLBL3MBTL1GAAKMT2A
	SCHEMBL8819678	0.75	MAPT (0.58)	ARPOLBGAAKMT2AALDH1A1
	SCHEMBL848277	0.75	TSHR (0.52)	TSHRPOLBALKBH5L3MBTL1GAA
	SCHEMBL10291202	0.75	AR (0.44)	TSHRARPOLBL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.