Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826970 | 0.85 | PKM (0.59) | ALDH1A1KMT2AGAAMAPTAR | |
| SCHEMBL850306 | 0.85 | TSHR (0.55) | ALDH1A1KMT2AGAAMAPTAR | |
| SCHEMBL849330 | 0.81 | AR (0.46) | ALDH1A1KMT2AGAAMAPTAR | |
| SCHEMBL16359018 | 0.80 | AR (0.45) | ALDH1A1KMT2AGAAMAPTAR | |
| SCHEMBL8819678 | 0.79 | MAPT (0.58) | ALDH1A1KMT2AGAAMAPTAR | |
| SCHEMBL10291202 | 0.79 | AR (0.44) | ALDH1A1KMT2AGAAMAPTAR | |
| SCHEMBL879903 | 0.79 | AR (0.42) | ALDH1A1KMT2AGAAMAPTAR | |
| SCHEMBL849854 | 0.79 | TSHR (0.54) | ALDH1A1KMT2AGAAMAPTAR | |
| SCHEMBL11842431 | 0.77 | L3MBTL1 (0.64) | ALDH1A1KMT2AGAAMAPTAR | |
| SCHEMBL11479045 | 0.77 | KMT2A (0.59) | ALDH1A1KMT2AGAAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-A1 | SPIROIMIDAZOLONE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-03-28 | — | — | EP | disclosed |