Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316723 | 0.72 | PTGS1 (0.38) | KDM4EMEN1ALDH1A1LMNAGLA | |
| SCHEMBL7548622 | 0.70 | KDM4E (0.39) | KDM4EMEN1ALDH1A1LMNAGLA | |
| SCHEMBL8994449 | 0.70 | KDM4E (0.39) | KDM4EMEN1ALDH1A1LMNAGLA | |
| SCHEMBL8799002 | 0.69 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL9217692 | 0.69 | ALDH1A1 (0.38) | KDM4EMEN1ALDH1A1LMNAGLA | |
| SCHEMBL7508068 | 0.69 | KDM4E (0.37) | KDM4EMEN1ALDH1A1LMNAGLA | |
| SCHEMBL7499361 | 0.69 | KDM4E (0.37) | KDM4EMEN1ALDH1A1LMNAGLA | |
| SCHEMBL9057679 | 0.68 | HTT (0.36) | KDM4EMEN1ALDH1A1LMNAGLA | |
| SCHEMBL9211327 | 0.67 | MAPT (0.39) | KDM4EMEN1ALDH1A1LMNAGLA | |
| SCHEMBL9423599 | 0.66 | KDM4E (0.38) | KDM4EMEN1ALDH1A1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481182-B1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID CO (US) | 1997-01-29 | — | — | EP | claimed |
| US-5157047-A | Miticides | AMERICAN CYANAMID COMPANY (US) | 1992-10-20 | — | — | US | claimed |
| EP-0481182-A1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-22 | — | — | EP | claimed |