SCHEMBL8799062

SCHEMBL8799062

COC(=O)Oc1cccc(C=O)n1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TERT O14746 12/20 0.43
CCR1 P32246 1/20 0.37
FGFR4 P22455 3/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPK8 P45983 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6225917 0.84 KDM4E (0.48) KDM4EHPGDHSD17B10MAPK8
SCHEMBL4713939 0.80 ALDH1A1 (0.54) KDM4EHPGDHSD17B10
SCHEMBL28475692 0.79 MEN1 (0.41) TERTCCR1FGFR4
SCHEMBL6223869 0.79 KDM4E (0.44) KDM4EHPGDHSD17B10MAPK8
SCHEMBL29432664 0.78 IDH1 (0.47) TERTCCR1
SCHEMBL506568 0.78 IDH1 (0.47) TERTCCR1
SCHEMBL4707883 0.76 XIAP (0.45) KDM4EHPGDHSD17B10MAPK8
SCHEMBL9326030 0.76 L3MBTL1 (0.52) KDM4EHPGDHSD17B10MAPK8
SCHEMBL594437 0.74 ALDH1A3 (0.40) TERTCCR1
SCHEMBL29432650 0.74 ALDH1A3 (0.40) TERTCCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0763033-A1 IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1997-03-19 EP claimed
WO-1995032198-A1 IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-11-30 WO claimed