Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 3/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6225917 | 0.87 | KDM4E (0.48) | KDM4EHSD17B10HPGDMAPK8MTNR1A | |
| SCHEMBL8151882 | 0.81 | NOS3 (0.42) | XIAPBIRC2NOS3NOS2MCHR1 | |
| SCHEMBL6223869 | 0.81 | KDM4E (0.44) | KDM4EHSD17B10HPGDMAPK8MTNR1A | |
| SCHEMBL2780205 | 0.79 | ASIC3 (0.39) | XIAPBIRC2NOS3NOS2MCHR1 | |
| SCHEMBL20557225 | 0.79 | MEN1 (0.45) | XIAPBIRC2NOS3NOS2MCHR1 | |
| SCHEMBL9326030 | 0.79 | L3MBTL1 (0.52) | KDM4EHSD17B10HPGDMAPTMAPK8 | |
| SCHEMBL22556890 | 0.77 | ACHE (0.41) | XIAPBIRC2NOS3NOS2MCHR1 | |
| SCHEMBL5203500 | 0.77 | MTNR1A (0.46) | MCHR1HSD17B10MTNR1AMTNR1BALDH1A1 | |
| Acetic Acid SCHEMBL28232255 | 0.76 | POLB (0.43) | XIAPBIRC2NOS3NOS2MCHR1 | |
| SCHEMBL8799062 | 0.76 | TERT (0.43) | KDM4EHSD17B10HPGDMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943222-A1 | ANTIBACTERIAL ACTIVE 5-CHINOLIN DERIVATIVE | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007042325-A1 | ANTIBACTERIAL ACTIVE 5-CHINOLIN DERIVATIVE | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2007-04-19 | — | — | WO | disclosed |