Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11325997 | 0.83 | ALDH1A1 (0.71) | ALDH1A1TDP1TP53MAPTADAM17 | |
| SCHEMBL15791835 | 0.82 | MAPT (0.70) | ALDH1A1TDP1TP53MAPTTSHR | |
| SCHEMBL11268298 | 0.81 | NPC1 (0.58) | ALDH1A1TDP1TP53MAPTGAA | |
| SCHEMBL13822548 | 0.81 | MAPT (0.47) | ALDH1A1TDP1TP53MAPTGAA | |
| SCHEMBL3080578 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TDP1TP53MAPTTSHR | |
| SCHEMBL25236464 | 0.77 | MAPT (0.58) | ALDH1A1TDP1TP53MAPTTSHR | |
| SCHEMBL25285696 | 0.77 | MAPT (0.66) | ALDH1A1TDP1TP53MAPTCA1 | |
| SCHEMBL11722207 | 0.76 | KMT2A (0.44) | ALDH1A1MAPTTSHRCA2CYP2C19 | |
| SCHEMBL5679198 | 0.75 | MMP2 (0.63) | ALDH1A1TDP1GAATSHRDHFR | |
| SCHEMBL3479371 | 0.75 | ALDH1A1 (0.69) | ALDH1A1TDP1GAATSHRDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507171-B1 | Sulfonylaminocarbonyltriazolinones with oxygen-bound substituents | BAYER AG (DE) | 1997-10-01 | — | — | EP | disclosed |
| EP-0524482-B1 | Substituted triazoles and their use as herbicides | BAYER AG (DE) | 1994-06-08 | — | — | EP | disclosed |
| EP-0586418-A1 | SUBSTITUTED TRIAZOLINONES | BAYER AG (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5273958-A | A 1-(1-alkyl-3-phenylpropylaminocarbonyl)-3-alkyl-4-amino-5-oxo or thio-2-1H-1,2,4-triazoline | BAYER AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |
| US-5217522-A | HERBICIDAL SULPHONYLGUANIDINOAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1993-06-08 | — | — | US | disclosed |
| EP-0524482-A1 | Substituted triazoles and their use as herbicides | BAYER AG (DE) | 1993-01-27 | — | — | EP | disclosed |
| EP-0517052-A1 | Substituted imidazolinyl-pyrimidines | BAYER AG (DE) | 1992-12-09 | — | — | EP | disclosed |
| WO-1992020663-A1 | SUBSTITUTED TRIAZOLINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-26 | — | — | WO | disclosed |
| EP-0513621-A1 | Substituted triazolinones | BAYER AG (DE) | 1992-11-19 | — | — | EP | disclosed |
| EP-0511569-A1 | Substituted triazolinone | BAYER AG (DE) | 1992-11-04 | — | — | EP | disclosed |
| US-4094664-A | 6-AMINO-O-TOLUIC ACID, HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1978-06-13 | — | — | US | disclosed |
| US-4067722-A | COPPER(II) COMPLEXES OF 2,3:4,6-DI-O-(SUBSTITUTED)-ALPHA-L-XYLO-2-HEXULOFURANOSONIC ACID | HOFFMANN-LA ROCHE INC. (US) | 1978-01-10 | — | — | US | disclosed |
| US-4029687-A | HERBICIDES | CIBA-GEIGY AG (CH) | 1977-06-14 | — | — | US | disclosed |
| US-4028089-A | BENZOXAZOLINYLIDENE-MALONITRILE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 1977-06-07 | — | — | US | disclosed |
| US-4014678-A | 1-(3,7-Dimethyloctyl)-1(2-propenyl)-and 1(2-propynyl)-piperidinium bromides as plant growth regulants | HOFFMANN-LA ROCHE INC. (US) | 1977-03-29 | — | — | US | disclosed |
| US-4007206-A | HERBICIDE, PLANT GROWTH REGULATOR | HOFFMANN-LA ROCHE INC. (US) | 1977-02-08 | — | — | US | disclosed |
| US-4004914-A | HERBICIDES | CIBA-GEIGY AG (CH) | 1977-01-25 | — | — | US | disclosed |
| US-3981860-A | PLANT GROWTH REGULATORS, HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1976-09-21 | — | — | US | disclosed |
| US-3951641-A | Use of N-(4-isopropoxy-3-chlorophenyl)-N'-methyl-N'-methoxyurea for control of weeds in maize cultures | CIBA-GEIGY AG (CH) | 1976-04-20 | — | — | US | disclosed |
| US-3931149-A | PLANT GROWTH REGULATORS | HOFFMANN-LA ROCHE INC. (US) | 1976-01-06 | — | — | US | disclosed |