Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817437 | 0.87 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTNPSR1KDM4E | |
| SCHEMBL7827083 | 0.87 | TYK2 (0.47) | ALDH1A1LMNAMAPTNPSR1KDM4E | |
| SCHEMBL7815641 | 0.83 | TDP1 (0.43) | ALDH1A1LMNAMAPTNPSR1HTT | |
| SCHEMBL7824213 | 0.83 | RAB9A (0.41) | ALDH1A1LMNAMAPTNPSR1HTT | |
| SCHEMBL7816325 | 0.82 | MAOB (0.38) | ALDH1A1LMNAMAPTNPSR1KDM4E | |
| SCHEMBL7827508 | 0.80 | GPR35 (0.50) | ALDH1A1MAPTKDM4EHTTPDK1 | |
| SCHEMBL8799382 | 0.79 | TYK2 (0.37) | ALDH1A1LMNAMAPTNPSR1RAB9A | |
| SCHEMBL7816537 | 0.78 | GPR35 (0.41) | ALDH1A1LMNAMAPTNPSR1PDK1 | |
| SCHEMBL8799550 | 0.78 | ALDH1A1 (0.38) | ALDH1A1LMNAMAPTNPSR1KDM4E | |
| SCHEMBL7825378 | 0.77 | GAA (0.42) | ALDH1A1LMNAMAPTNPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029907-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-09 | — | — | WO | disclosed |