Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.55 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27028620 | 0.86 | PDK1 (0.41) | PDK1MEN1KMT2AMAPTLMNA | |
| SCHEMBL8798263 | 0.79 | PDK1 (0.58) | PDK1XDHTDP1MEN1KMT2A | |
| SCHEMBL6809251 | 0.79 | PDK1 (0.58) | PDK1CYP19A1TDP1MEN1KMT2A | |
| SCHEMBL29749825 | 0.79 | PDK1 (0.58) | PDK1CYP19A1TDP1MEN1KMT2A | |
| SCHEMBL8799454 | 0.78 | ALDH1A1 (0.39) | PDK1MEN1KMT2AMAPTLMNA | |
| SCHEMBL16958967 | 0.78 | PDK1 (0.57) | PDK1XDHCYP19A1TDP1MEN1 | |
| SCHEMBL19175613 | 0.78 | PDK1 (0.61) | PDK1XDHKMT2AMAPTNPC1 | |
| SCHEMBL14136388 | 0.78 | PDK1 (0.57) | PDK1XDHCYP19A1TDP1MEN1 | |
| SCHEMBL3043316 | 0.78 | PDK1 (0.57) | PDK1XDHCYP19A1TDP1MEN1 | |
| SCHEMBL1136078 | 0.78 | PDK1 (0.57) | PDK1XDHCYP19A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025051129-A1 | ARYL HETEROCYCLIC SLC7A11 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海深势唯思科技有限责任公司 | 2025-03-13 | — | — | WO | disclosed |
| CN-119552124-A | Aryl heterocycle SLC7A11 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2025-03-04 | — | — | CN | disclosed |
| EP-0482771-B1 | Heterocyclic acids | ZENECA LTD (GB) | 1997-06-18 | — | — | EP | disclosed |
| US-5410064-A | Thromboxane A2 antagonists and inhibitors of thromboxane A2 synthase | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-04-25 | — | — | US | disclosed |
| US-5219874-A | Heterocyclic acids | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-15 | — | — | US | disclosed |
| EP-0482771-A2 | Heterocyclic acids | ZENECA LIMITED (GB) | 1992-04-29 | — | — | EP | disclosed |