Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 4/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27261807 | 0.89 | PPARA (0.47) | CYP4F2CYP4A11 | |
| SCHEMBL6755952 | 0.82 | ALDH1A1 (0.43) | KMT2AMEN1 | |
| SCHEMBL9122184 | 0.76 | CYP4F2 (0.36) | CYP4F2CYP4A11KMT2AMEN1HCRTR1 | |
| SCHEMBL9118767 | 0.76 | CYP4F2 (0.50) | CYP4F2CYP4A11 | |
| SCHEMBL9119417 | 0.76 | CYP4F2 (0.50) | CYP4F2CYP4A11 | |
| SCHEMBL6224100 | 0.75 | NLRP3 (0.46) | KMT2AMEN1 | |
| SCHEMBL22112689 | 0.75 | NLRP3 (0.46) | KMT2AMEN1 | |
| SCHEMBL28019768 | 0.75 | KMT2A (0.46) | KMT2AMEN1 | |
| SCHEMBL8798769 | 0.75 | MEN1 (0.47) | KMT2AMEN1 | |
| SCHEMBL8800306 | 0.75 | ALDH1A1 (0.44) | CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755381-A1 | SUBSTITUTED PYRIDINE LEUKOTRIENE B 4 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028386-A1 | SUBSTITUTED PYRIDINE LEUKOTRIENE B4 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1995-10-26 | — | — | WO | disclosed |