Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827125 | 0.87 | MAPT (0.43) | RORCLMNAMAPTHTTNPC1 | |
| SCHEMBL8798812 | 0.85 | MEN1 (0.40) | MAPTHTTNPC1RAB9AGPR35 | |
| SCHEMBL7830415 | 0.81 | POLB (0.41) | RORCLMNAMAPTNPC1MAPK1 | |
| SCHEMBL7831524 | 0.77 | MAPT (0.48) | RORCLMNAMAPTHTTMAPK1 | |
| SCHEMBL8800344 | 0.74 | EYA3 (0.44) | LMNANPC1RAB9AGPR35 | |
| SCHEMBL7828909 | 0.73 | THRB (0.44) | LMNAMAPTHTTNPC1MAPK1 | |
| SCHEMBL8342148 | 0.71 | MAPT (0.44) | LMNAMAPTNPC1GPR35ALDH1A1 | |
| SCHEMBL7816589 | 0.71 | MAPT (0.44) | LMNAMAPTNPC1GPR35ALDH1A1 | |
| SCHEMBL7826306 | 0.70 | GAA (0.45) | LMNAMAPTHTTNPC1RAB9A | |
| SCHEMBL5725938 | 0.70 | TDP1 (0.58) | LMNAMAPTHTTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |