Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 2/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.43 |
| ▸ | TTR | P02766 | 3/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798812 | 0.87 | MEN1 (0.40) | GPR35TTRSLC16A3MEN1KMT2A | |
| SCHEMBL7828069 | 0.85 | GPR35 (0.46) | CYP2C19GPR35SLC16A3MEN1KMT2A | |
| SCHEMBL7828909 | 0.84 | THRB (0.44) | SLC16A3MEN1KMT2ALMNANPC1 | |
| SCHEMBL8804997 | 0.83 | GPR35 (0.39) | GPR35SLC16A3MEN1KMT2APLK1 | |
| SCHEMBL8341922 | 0.76 | GPR35 (0.42) | GPR35SLC16A3MEN1KMT2ALMNA | |
| SCHEMBL7817291 | 0.75 | RAB9A (0.41) | SLC16A3MEN1KMT2ALMNAPLK1 | |
| SCHEMBL7826306 | 0.74 | GAA (0.45) | GPR35MEN1KMT2ALMNAPDE4A | |
| SCHEMBL7816337 | 0.74 | KDM4E (0.41) | GPR35SLC16A3MEN1KMT2ALMNA | |
| SCHEMBL8799712 | 0.74 | RORC (0.38) | GPR35LMNANPC1RAB9A | |
| SCHEMBL7823933 | 0.73 | MAPT (0.48) | GPR35MEN1KMT2ALMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029907-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-09 | — | — | WO | disclosed |