Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7542152 | 0.89 | CDK2 (0.44) | CDK2HCRTR1HCRTR2KCNK3KCNK9 | |
| SCHEMBL8798631 | 0.84 | RORB (0.47) | CDK2HSD17B10 | |
| SCHEMBL8610774 | 0.81 | CNR2 (0.49) | CDK2HTTHSD17B10 | |
| SCHEMBL7552945 | 0.79 | ALDH1A1 (0.49) | CDK2HTT | |
| SCHEMBL8800986 | 0.78 | RECQL (0.48) | CDK2 | |
| SCHEMBL8799820 | 0.77 | ALDH1A1 (0.40) | HSD17B10ELANE | |
| SCHEMBL7548471 | 0.77 | MAPK13 (0.41) | CDK2ELANE | |
| SCHEMBL20641943 | 0.77 | SCN9A (0.40) | CDK2HCRTR1HCRTR2KCNK3KCNK9 | |
| SCHEMBL5784212 | 0.77 | ELANE (0.52) | CDK2HCRTR1HCRTR2KCNK3KCNK9 | |
| SCHEMBL7543771 | 0.74 | BCAT2 (0.44) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |