Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548771 | 0.89 | BCAT2 (0.46) | BCAT2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8610881 | 0.83 | ADORA3 (0.44) | BCAT2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8800986 | 0.82 | RECQL (0.48) | MAPK14NAPRTALDH1A1LMNAKMT2A | |
| SCHEMBL8799820 | 0.81 | ALDH1A1 (0.40) | MAPK13MAPK12MAPK11MAPK14NAPRT | |
| SCHEMBL7548471 | 0.81 | MAPK13 (0.41) | MAPK13MAPK12MAPK11MAPK14NAPRT | |
| SCHEMBL7552945 | 0.81 | ALDH1A1 (0.49) | NAPRTALDH1A1HTTSMN1; SMN2PRKCI | |
| SCHEMBL8798631 | 0.77 | RORB (0.47) | MAPK13MAPK12MAPK11MAPK14LMNA | |
| SCHEMBL8610774 | 0.77 | CNR2 (0.49) | MAPK14NAPRTKDRLMNAHTT | |
| SCHEMBL9060466 | 0.76 | NOS3 (0.40) | MAPK13MAPK12MAPK11MAPK14NAPRT | |
| SCHEMBL8799888 | 0.74 | CDK2 (0.43) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049708-A9 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | — | 1998-05-22 | — | — | WO | disclosed |
| US-5719278-A | TREATING EXCESS RENAL REABSORPTION OF WATER | AMERICAN CYANAMID COMPANY (US) | 1998-02-17 | — | — | US | disclosed |