Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 5/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GHSR | Q92847 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827138 | 0.87 | KMT2A (0.38) | JAK2JAK1TYK2ALDH1A1KMT2A | |
| SCHEMBL8341865 | 0.81 | KMT2A (0.41) | JAK2JAK1TYK2ALDH1A1GHSR | |
| SCHEMBL8800035 | 0.81 | GHSR (0.40) | ITGB1ITGA4GHSRSMN1; SMN2KMT2A | |
| SCHEMBL7827960 | 0.80 | ALDH1A1 (0.40) | ITGB1ITGA4JAK2JAK1TYK2 | |
| SCHEMBL7816603 | 0.79 | MEN1 (0.38) | ITGB1ITGA4GHSRSMN1; SMN2KMT2A | |
| SCHEMBL8800246 | 0.79 | ALDH1A1 (0.38) | ITGB1ITGA4JAK2JAK1TYK2 | |
| SCHEMBL7817213 | 0.79 | MEN1 (0.39) | ITGB1ITGA4JAK2JAK1TYK2 | |
| SCHEMBL8341719 | 0.78 | MEN1 (0.40) | ITGB1ITGA4ALDH1A1GHSRSMN1; SMN2 | |
| SCHEMBL8800451 | 0.76 | TYK2 (0.42) | ITGB1ITGA4TYK2ALDH1A1GHSR | |
| SCHEMBL8799666 | 0.76 | GHSR (0.42) | ALDH1A1GHSRKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |