Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 7/20 | 0.41 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 3/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800035 | 0.95 | GHSR (0.40) | ITGB1ITGA4ITGA2ITGB7GHSR | |
| SCHEMBL8801121 | 0.90 | GPR35 (0.39) | TYK2GHSRALDH1A1MAPTLMNA | |
| SCHEMBL8799666 | 0.89 | GHSR (0.42) | GHSRALDH1A1MAPTNPSR1L3MBTL1 | |
| SCHEMBL8800075 | 0.88 | ITGB1 (0.39) | ITGB1ITGA4ALDH1A1MAPTLMNA | |
| SCHEMBL8799550 | 0.88 | ALDH1A1 (0.38) | ALDH1A1MAPTLMNANPSR1KDM4E | |
| SCHEMBL8799385 | 0.87 | GHSR (0.38) | ITGB1ITGA4ITGB7GHSRALDH1A1 | |
| SCHEMBL7816603 | 0.86 | MEN1 (0.38) | ITGB1ITGA4GHSRMAPTSMN1; SMN2 | |
| SCHEMBL7817213 | 0.86 | MEN1 (0.39) | TYK2ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL8799508 | 0.85 | GPR35 (0.41) | TYK2GHSRMEN1KMT2A | |
| SCHEMBL8798653 | 0.85 | PTGS2 (0.40) | GHSRALDH1A1MAPTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |