Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800035 | 0.92 | GHSR (0.40) | GHSRMEN1KMT2APOLBMAPT | |
| SCHEMBL8798653 | 0.90 | PTGS2 (0.40) | GHSRPTGS2MEN1KMT2AGAA | |
| SCHEMBL8800451 | 0.89 | TYK2 (0.42) | GHSRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8800324 | 0.88 | MAOB (0.43) | GHSRMEN1KMT2APOLBMAPT | |
| SCHEMBL8801121 | 0.87 | GPR35 (0.39) | GHSRMEN1KMT2APOLBMAPT | |
| SCHEMBL8799385 | 0.84 | GHSR (0.38) | GHSRALDH1A1 | |
| SCHEMBL7816603 | 0.84 | MEN1 (0.38) | GHSRMEN1KMT2APOLBMAPT | |
| SCHEMBL7817213 | 0.83 | MEN1 (0.39) | GHSRMEN1KMT2APOLBMAPT | |
| SCHEMBL8799508 | 0.83 | GPR35 (0.41) | GHSRPTGS2MEN1KMT2APOLB | |
| SCHEMBL8799777 | 0.80 | GPR35 (0.45) | GHSRMEN1KMT2AGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |