Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 9/20 | 0.50 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 3/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663687 | 0.97 | CTSD (0.47) | CTSLTACR1CTSBCTSSCTSK | |
| SCHEMBL8944981 | 0.92 | CTSD (0.48) | CTSLCTSBCTSKMMEECE1 | |
| SCHEMBL7295499 | 0.89 | CTSL (0.51) | CTSLTACR1CTSBCTSSCTSK | |
| SCHEMBL8661021 | 0.88 | SMN1; SMN2 (0.48) | CTSLCTSBMMEECE1 | |
| SCHEMBL8662047 | 0.88 | PSMB1 (0.54) | CTSLCTSBCTSSCTSK | |
| SCHEMBL8664364 | 0.88 | CTSD (0.49) | CTSLCTSBCTSKCTSD | |
| SCHEMBL8660791 | 0.84 | CTRB1 (0.50) | CTSLTACR1CTSBCTSSCTSK | |
| SCHEMBL8665786 | 0.81 | CTSD (0.48) | CTSLCTSDKDM1A | |
| SCHEMBL8944978 | 0.81 | CTSS (0.56) | CTSLCTSBCTSSCTSD | |
| SCHEMBL8669118 | 0.81 | CTSD (0.49) | CTSLCTSBCTSSCTSKMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587388-A | AIDS; VIRICIDES | LUCKY LIMITED (KR) | 1996-12-24 | — | — | US | disclosed |
| EP-0601486-A1 | Cis-epoxide derivatives useful as irreversible HIV protease inhibitors and process and intermediates for their preparation | LUCKY LTD. (KR) | 1994-06-15 | — | — | EP | disclosed |