Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18940340 | 0.73 | CYP19A1 (0.49) | CYP19A1TBXAS1CYP11B1CYP11B2 | |
| SCHEMBL27978584 | 0.72 | CYP2A6 (0.51) | MEN1KMT2A | |
| SCHEMBL5655551 | 0.72 | CYP19A1 (0.71) | CYP19A1KMT2ATBXAS1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL22283559 | 0.72 | CYP19A1 (0.48) | CYP19A1MEN1KMT2ATBXAS1CYP11B1 | |
| SCHEMBL6169029 | 0.72 | CYP2A6 (0.44) | CYP19A1MEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL1540078 | 0.71 | PIM1 (0.52) | MEN1KMT2ADRD4 | |
| SCHEMBL7088292 | 0.70 | CYP24A1 (0.63) | TBXAS1CYP11B1CYP11B2 | |
| SCHEMBL1122018 | 0.70 | NOS3 (0.55) | TBXAS1CYP11B1CYP11B2 | |
| SCHEMBL8801068 | 0.70 | GPR84 (0.51) | MEN1KMT2A | |
| SCHEMBL10461655 | 0.69 | CYP19A1 (0.51) | CYP19A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0779887-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES HAVING CGMP-PHOSPHODISTERASE INHIBITING ACTIVITY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |