Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799883 | 0.81 | HTR1A (0.48) | GPR84MAPTMEN1KMT2ALMNA | |
| SCHEMBL12758951 | 0.77 | HRH3 (0.56) | GPR84MAPTMEN1KMT2ALMNA | |
| SCHEMBL4470856 | 0.77 | MAPT (0.52) | GPR84MAPTMEN1KMT2ALMNA | |
| SCHEMBL11354778 | 0.76 | GPR84 (0.44) | GPR84MAPTMEN1KMT2ALMNA | |
| SCHEMBL8837552 | 0.74 | LMNA (0.61) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL27978584 | 0.72 | CYP2A6 (0.51) | GPR84MAPTMEN1KMT2ATDP1 | |
| SCHEMBL2157305 | 0.72 | TDP1 (0.60) | TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL14044219 | 0.71 | MAPT (0.69) | MAPTMEN1KMT2ALMNATDP1 | |
| SCHEMBL8800534 | 0.70 | CYP19A1 (0.43) | MEN1KMT2A | |
| SCHEMBL7091473 | 0.69 | CDK4 (0.46) | MAPTMEN1KMT2ATDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0779887-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES HAVING CGMP-PHOSPHODISTERASE INHIBITING ACTIVITY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |