Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086183 | 0.90 | TP53 (0.35) | ALDH1A1KDM4ETP53SMN1; SMN2KMT2A | |
| SCHEMBL8799402 | 0.90 | S1PR3 (0.37) | ALDH1A1KMT2A | |
| SCHEMBL6961698 | 0.90 | S1PR3 (0.38) | ALDH1A1KDM4E | |
| SCHEMBL8800407 | 0.90 | MEN1 (0.33) | ALDH1A1KDM4EBRD4TP53TSHR | |
| SCHEMBL8800655 | 0.87 | CFTR (0.41) | ALDH1A1KDM4ECYP1A2HTTMAPK1 | |
| SCHEMBL6975584 | 0.85 | TDP1 (0.34) | PTGDR2ALDH1A1KDM4ETSHRCYP1A2 | |
| SCHEMBL7084666 | 0.84 | SLC18A3 (0.38) | ALDH1A1TP53TSHRCYP1A2HPGD | |
| SCHEMBL7084768 | 0.84 | PTGDR2 (0.36) | PTGDR2ALDH1A1KDM4EBRD4TP53 | |
| SCHEMBL8801330 | 0.83 | KDM4E (0.38) | PTGDR2ALDH1A1KDM4EALOX5APL3MBTL1 | |
| SCHEMBL7084491 | 0.82 | CYP1A2 (0.40) | PTGDR2ALDH1A1KDM4EBRD4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |