Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 9/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961698 | 0.93 | S1PR3 (0.38) | S1PR3ALDH1A1SYK | |
| SCHEMBL8800780 | 0.90 | PTGDR2 (0.35) | KMT2AALDH1A1 | |
| SCHEMBL7086183 | 0.90 | TP53 (0.35) | GRIN1GRIN2BSLC6A9RXFP1KMT2A | |
| SCHEMBL8800655 | 0.87 | CFTR (0.41) | S1PR3KMT2AALDH1A1 | |
| SCHEMBL8799639 | 0.86 | GRIN1 (0.35) | GRIN1GRIN2BSLC6A9KMT2AALDH1A1 | |
| SCHEMBL8800407 | 0.86 | MEN1 (0.33) | S1PR3KMT2AALDH1A1 | |
| SCHEMBL6973156 | 0.86 | S1PR3 (0.38) | S1PR3GRIN1GRIN2BSLC6A9RXFP1 | |
| SCHEMBL8800250 | 0.85 | SLC6A9 (0.34) | SLC6A9ALDH1A1PABPC1 | |
| SCHEMBL7084823 | 0.84 | S1PR3 (0.39) | S1PR3GRIN1GRIN2BSLC6A9KMT2A | |
| SCHEMBL6974251 | 0.84 | GRIN1 (0.38) | S1PR3GRIN1GRIN2BKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |