Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22397824 | 0.98 | CACNA1H (0.39) | CACNA1HLOXL2LOX | |
| SCHEMBL30720841 | 0.76 | FABP4 (0.30) | — | |
| SCHEMBL28838831 | 0.72 | TAAR1 (0.43) | — | |
| SCHEMBL5897349 | 0.72 | ALDH1A1 (0.39) | — | |
| SCHEMBL27086882 | 0.70 | FABP4 (0.33) | CACNA1H | |
| Hydrochloric Acid SCHEMBL28813143 | 0.70 | TAAR1 (0.41) | — | |
| SCHEMBL28236812 | 0.70 | NPBWR1 (0.47) | LOXL2LOX | |
| Hydrochloric Acid SCHEMBL31417166 | 0.70 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1 | |
| SCHEMBL30720847 | 0.69 | — | — | |
| SCHEMBL25936006 | 0.69 | CACNA1H (0.51) | CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1313463-C | Benzopyran derivatives substituted with secondary amines including imidazole, their preparation and pharmaceutical compositions containing them | KOREA RES INST CHEM TECH (KR) | 2007-05-02 | — | — | CN | disclosed |
| CN-1675202-A | Benzopyran derivatives substituted with secondary amines including imidazole, their preparation and pharmaceutical compositions containing them | KOREA RES INST CHEM TECH (KR) | 2005-09-28 | — | — | CN | disclosed |
| EP-0772601-A1 | 4,5-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-05-14 | — | — | EP | disclosed |