Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 16/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.40 |
| ▸ | PLA2G2E | Q9NZK7 | 3/20 | 0.40 |
| ▸ | PLA2G2F | Q9BZM2 | 2/20 | 0.40 |
| ▸ | PLA2G2D | Q9UNK4 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802251 | 0.90 | GABRP (0.37) | PLA2G2APLA2G10PLA2G2EPLA2G2FPLA2G2D | |
| SCHEMBL8802594 | 0.87 | LTB4R (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8801516 | 0.87 | LTB4R (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8805234 | 0.86 | TSPO (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8472963 | 0.86 | GABRP (0.52) | PLA2G2APLA2G10PLA2G2EPLA2G2FPLA2G2D | |
| SCHEMBL8801270 | 0.85 | GABRP (0.36) | PLA2G2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8803022 | 0.83 | GABRP (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8802720 | 0.83 | GABRP (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8801428 | 0.80 | GABRA1 (0.62) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8805512 | 0.79 | GABRP (0.42) | PLA2G2AGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805810-A1 | NOVEL 9H-PYRIDO 3,4-B]INDOL DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022989-A1 | NOVEL 9H-PYRIDO[3,4-B]INDOL DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-08-01 | — | — | WO | disclosed |