Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800805 | 0.86 | PPARG (0.41) | PPARGPPARALAP3CYP2D6CYP2C9 | |
| SCHEMBL8802092 | 0.81 | PPARG (0.38) | PPARGPPARAMEN1CYP2D6CYP2C9 | |
| SCHEMBL8800961 | 0.81 | TSHR (0.41) | PPARGPPARAALDH1A1TSHRHPGD | |
| SCHEMBL8800892 | 0.80 | PPARG (0.39) | PPARGPPARAPKMMEN1CYP2D6 | |
| SCHEMBL9570425 | 0.79 | LMNA (0.38) | PPARGPPARAMEN1CYP2D6CYP2C9 | |
| SCHEMBL8801699 | 0.77 | PPARG (0.44) | PPARGPPARAMEN1CYP1A2KMT2A | |
| Hydrochloric Acid SCHEMBL8800525 | 0.76 | PPARG (0.43) | PPARGPPARAMEN1CYP1A2KMT2A | |
| SCHEMBL27670994 | 0.75 | SLC1A3 (0.47) | PPARGPPARASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL11601023 | 0.74 | TSHR (0.43) | KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL27603064 | 0.73 | CES2 (0.51) | ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522956-B1 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI SA (FR) | 1997-02-05 | — | — | EP | disclosed |
| EP-0522956-A2 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI (FR) | 1993-01-13 | — | — | EP | disclosed |