Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570422 | 0.81 | POLB (0.42) | LMNAPOLBTDP1PPARGPPARA | |
| SCHEMBL8800892 | 0.81 | PPARG (0.39) | LMNAPPARGPPARAMAPTALDH1A1 | |
| SCHEMBL8800805 | 0.80 | PPARG (0.41) | LMNAPPARGPPARAMAPTALDH1A1 | |
| SCHEMBL8801705 | 0.79 | PPARG (0.40) | PPARGPPARAMAPTALDH1A1TSHR | |
| SCHEMBL8802092 | 0.76 | PPARG (0.38) | LMNAPOLBPPARGPPARAMAPT | |
| SCHEMBL8800961 | 0.75 | TSHR (0.41) | POLBPPARGPPARAALDH1A1TSHR | |
| SCHEMBL9570349 | 0.71 | MEN1 (0.41) | LMNAALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL11601023 | 0.69 | TSHR (0.43) | POLBTDP1MAPTALDH1A1TSHR | |
| SCHEMBL27603064 | 0.68 | CES2 (0.51) | POLBTDP1MAPTALDH1A1TSHR | |
| SCHEMBL16377671 | 0.68 | PKM (0.42) | POLBTDP1MAPTTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522956-A2 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI (FR) | 1993-01-13 | — | — | EP | disclosed |