Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570425 | 0.81 | LMNA (0.38) | PPARGPPARATSHRMAPTALDH1A1 | |
| SCHEMBL8800805 | 0.81 | PPARG (0.41) | PPARGPPARATSHRMAPTNPC1 | |
| SCHEMBL8801705 | 0.80 | PPARG (0.40) | PPARGPPARATSHRMAPTALDH1A1 | |
| SCHEMBL8800961 | 0.78 | TSHR (0.41) | PPARGPPARATSHRL3MBTL1ALDH1A1 | |
| SCHEMBL8802092 | 0.77 | PPARG (0.38) | PPARGPPARATSHRMAPTALDH1A1 | |
| SCHEMBL11601023 | 0.70 | TSHR (0.43) | TSHRMAPTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL27603064 | 0.69 | CES2 (0.51) | TSHRMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL8802018 | 0.68 | LMNA (0.38) | PPARGPPARATSHRL3MBTL1ALDH1A1 | |
| SCHEMBL11474849 | 0.68 | TSHR (0.42) | PPARGPPARATSHRMAPTL3MBTL1 | |
| SCHEMBL8801701 | 0.67 | MTNR1A (0.43) | TSHRMAPTNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580916-B1 | N(1) substituted pyrazino [2,3-c]-1,2,6-thiadiazine 2,2-dioxides and their use as pharmaceuticals | PRODESFARMA SA (ES) | 1997-03-05 | — | — | EP | claimed |