Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843190 | 0.84 | RECQL (0.38) | L3MBTL1RECQLMAPTPOLBGAA | |
| SCHEMBL8198330 | 0.82 | MAPT (0.38) | L3MBTL1RECQLMAPTPOLBGAA | |
| SCHEMBL8805455 | 0.79 | RECQL (0.38) | L3MBTL1RECQLMAPTPOLBGAA | |
| SCHEMBL4655364 | 0.79 | RECQL (0.44) | L3MBTL1RECQLMAPTPOLBGAA | |
| SCHEMBL7840106 | 0.78 | RECQL (0.38) | L3MBTL1RECQLMAPTPOLBGAA | |
| SCHEMBL8867161 | 0.77 | ALDH1A1 (0.42) | MAPTGAAKMT2AALDH1A1KDM4E | |
| SCHEMBL8801766 | 0.76 | L3MBTL1 (0.39) | L3MBTL1RECQLMAPTPOLBGAA | |
| SCHEMBL8801760 | 0.76 | L3MBTL1 (0.39) | L3MBTL1RECQLMAPTPOLBGAA | |
| Clothianidine SCHEMBL21215 | 0.73 | RECQL (0.39) | L3MBTL1RECQLMAPTPOLBGAA | |
| Clothianidine SCHEMBL312742 | 0.73 | RECQL (0.39) | L3MBTL1RECQLMAPTPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446913-B1 | Process for the preparation of chlorothiazole derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-06-04 | — | — | EP | disclosed |
| EP-0446913-A1 | Process for the preparation of chlorothiazole derivatives | Takeda Chemical Industries, Ltd. (JP) | 1991-09-18 | — | — | EP | disclosed |