Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4655364 | 0.81 | RECQL (0.44) | RECQLMAPTL3MBTL1GAAPOLB | |
| SCHEMBL9843190 | 0.79 | RECQL (0.38) | RECQLMAPTL3MBTL1GAAPOLB | |
| SCHEMBL8801770 | 0.78 | L3MBTL1 (0.39) | RECQLMAPTL3MBTL1GAAPOLB | |
| SCHEMBL8198330 | 0.77 | MAPT (0.38) | RECQLMAPTL3MBTL1GAAPOLB | |
| SCHEMBL9134253 | 0.76 | ALDH1A1 (0.42) | L3MBTL1GAAKMT2AALDH1A1LMNA | |
| SCHEMBL2958535 | 0.76 | CHRNB2 (0.41) | MAPTGAAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8805455 | 0.76 | RECQL (0.38) | RECQLMAPTL3MBTL1GAAPOLB | |
| SCHEMBL7840103 | 0.74 | RECQL (0.38) | RECQLMAPTL3MBTL1GAAPOLB | |
| SCHEMBL7840104 | 0.74 | RECQL (0.38) | RECQLMAPTL3MBTL1GAAPOLB | |
| SCHEMBL9852593 | 0.73 | MAPT (0.39) | RECQLMAPTL3MBTL1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471372-B1 | Novel substituted guanidine derivatives, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-6160126-A | Synthetic Intermediates for the preparation of N, N'-Di-substituted isothiourea derivatives and N-cyclic(methyl)-N'-Substituted isothiourea derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-12-12 | — | — | US | disclosed |
| US-5696256-A | CHEMICAL INTERMEDIATE FOR INSECTICIDES; MITICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-09 | — | — | US | disclosed |
| EP-0452782-B1 | Novel intermediates for preparing guanidine derivatives, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-01-15 | — | — | EP | disclosed |
| US-5256679-A | Pesticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| EP-0471372-A1 | Novel substituted guanidine derivatives, their preparation and use | Takeda Chemical Industries, Ltd. (JP) | 1992-02-19 | — | — | EP | disclosed |
| EP-0452782-A1 | Novel intermediates for preparing guanidine derivatives, their preparation and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-23 | — | — | EP | disclosed |