Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7036880 | 0.79 | CHRNB2 (0.42) | ALDH1A1CHRNB2CHRNA4MEN1KMT2A | |
| SCHEMBL2958531 | 0.78 | CHRNB2 (0.41) | ALDH1A1CHRNB2CHRNA4NPC1RAB9A | |
| SCHEMBL2958535 | 0.78 | CHRNB2 (0.41) | ALDH1A1CHRNB2CHRNA4NPC1RAB9A | |
| SCHEMBL8801770 | 0.77 | L3MBTL1 (0.39) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8867156 | 0.76 | ALDH1A1 (0.42) | ALDH1A1CHRNB2CHRNA4MEN1KMT2A | |
| SCHEMBL8867144 | 0.76 | ALDH1A1 (0.42) | ALDH1A1CHRNB2CHRNA4MEN1KMT2A | |
| SCHEMBL9727921 | 0.74 | CHRNB2 (0.42) | ALDH1A1CHRNB2CHRNA4MEN1KMT2A | |
| SCHEMBL9843035 | 0.70 | CHRNB2 (0.37) | ALDH1A1CHRNB2CHRNA4MEN1KMT2A | |
| SCHEMBL8191142 | 0.70 | ALDH1A1 (0.40) | ALDH1A1CHRNB2CHRNA4MEN1KMT2A | |
| SCHEMBL8803706 | 0.69 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AATMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633375-A | NONTOXIC TO HUMNAS, ANIMALS, FISH | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| US-5489603-A | CONTAINING NITROGEN HETEROCYCLIC RINGS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-06 | — | — | US | disclosed |
| EP-0493369-B1 | Guanidine derivatives, their production and insecticides | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-11-08 | — | — | EP | disclosed |
| EP-0665222-A1 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1995-08-02 | — | — | EP | disclosed |
| EP-0493369-A1 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1992-07-01 | — | — | EP | disclosed |
| US-5034404-A | Nitroguanidines as insecticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-07-23 | — | — | US | disclosed |