Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 4/20 | 0.64 |
| ▸ | ACHE | P22303 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | HTR3A | P46098 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803953 | 0.83 | HTR4 (0.60) | HTR4ACHEALDH1A1 | |
| SCHEMBL9117844 | 0.81 | HTR4 (0.70) | HTR4CYP3A4GLAMEN1ALDH1A1 | |
| SCHEMBL17709629 | 0.78 | ACHE (1.00) | HTR4ACHECYP3A4GLA | |
| SCHEMBL8803576 | 0.78 | HTR4 (0.54) | HTR4CYP3A4GLAMEN1ALDH1A1 | |
| SCHEMBL2579561 | 0.78 | HTR4 (1.00) | HTR4CYP3A4GLAMEN1ALDH1A1 | |
| SCHEMBL29386039 | 0.78 | HTR4 (1.00) | HTR4CYP3A4GLAMEN1ALDH1A1 | |
| SCHEMBL6774093 | 0.77 | CHRNB4 (0.50) | HTR4ACHECYP3A4GLA | |
| Hydrochloric Acid SCHEMBL22532550 | 0.77 | HTR4 (0.98) | HTR4CYP3A4GLAMEN1ALDH1A1 | |
| SCHEMBL29767008 | 0.76 | HTR4 (1.00) | HTR4CYP3A4GLAMEN1ALDH1A1 | |
| SCHEMBL548053 | 0.76 | HTR4 (1.00) | HTR4CYP3A4GLAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499995-B1 | Piperidine derivatives | NISSHIN FLOUR MILLING CO (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5246945-A | 5-hydroxytryptamine antagonist for nervous system disorders | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0499995-A2 | Piperidine derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-08-26 | — | — | EP | disclosed |