Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802995 | 0.83 | HTR4 (0.47) | HTR4ALDH1A1 | |
| SCHEMBL8801798 | 0.78 | HTR4 (0.64) | HTR4CYP3A4GLAMEN1ALDH1A1 | |
| SCHEMBL8801807 | 0.78 | GAA (0.52) | HTR4 | |
| SCHEMBL8295294 | 0.74 | HTR4 (0.47) | HTR4HTR3A | |
| Hydrochloric Acid SCHEMBL9345072 | 0.74 | HTR4 (0.61) | HTR4CYP3A4MEN1ALDH1A1CYP2D6 | |
| SCHEMBL8803626 | 0.73 | GRM1 (0.42) | ALDH1A1 | |
| SCHEMBL15652199 | 0.73 | MEN1 (0.66) | HTR4CYP3A4GLAMEN1ALDH1A1 | |
| SCHEMBL7202734 | 0.73 | HTR4 (0.57) | HTR4CYP3A4GLAMEN1ALDH1A1 | |
| SCHEMBL28749742 | 0.73 | HTR4 (0.65) | HTR4CYP3A4GLAMEN1ALDH1A1 | |
| SCHEMBL9117844 | 0.72 | HTR4 (0.70) | HTR4CYP3A4GLAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499995-B1 | Piperidine derivatives | NISSHIN FLOUR MILLING CO (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5246945-A | 5-hydroxytryptamine antagonist for nervous system disorders | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0499995-A2 | Piperidine derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-08-26 | — | — | EP | disclosed |