Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 20/20 | 0.52 |
| ▸ | LTB4R2 | Q9NPC1 | 18/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801516 | 0.90 | LTB4R (0.50) | LTB4RLTB4R2 | |
| SCHEMBL8802594 | 0.83 | LTB4R (0.42) | LTB4RLTB4R2 | |
| SCHEMBL8801953 | 0.81 | LTB4R (0.53) | LTB4RLTB4R2 | |
| SCHEMBL8801965 | 0.78 | LTB4R (0.38) | LTB4RLTB4R2 | |
| SCHEMBL8802166 | 0.78 | LTB4R (0.55) | LTB4RLTB4R2 | |
| SCHEMBL8805234 | 0.77 | TSPO (0.43) | LTB4RLTB4R2 | |
| SCHEMBL8801777 | 0.77 | LTB4R (0.56) | LTB4RLTB4R2 | |
| SCHEMBL8802251 | 0.76 | GABRP (0.37) | LTB4RLTB4R2 | |
| SCHEMBL8801888 | 0.76 | LTB4R (0.53) | LTB4RLTB4R2 | |
| SCHEMBL8802720 | 0.76 | GABRP (0.39) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805810-A1 | NOVEL 9H-PYRIDO 3,4-B]INDOL DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022989-A1 | NOVEL 9H-PYRIDO[3,4-B]INDOL DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-08-01 | — | — | WO | disclosed |