Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801762 | 0.90 | GAA (0.40) | GAATDP1ALDH1A1ELANEPOLB | |
| SCHEMBL8303404 | 0.77 | GAA (0.39) | GAATDP1ALDH1A1ELANEPOLB | |
| SCHEMBL6644261 | 0.72 | MEN1 (0.39) | GAATDP1ALDH1A1KDM4EPOLB | |
| SCHEMBL8803622 | 0.71 | ELANE (0.43) | GAATDP1ALDH1A1ELANEPOLB | |
| SCHEMBL7981672 | 0.69 | POLB (0.41) | GAATDP1ALDH1A1KDM4EELANE | |
| SCHEMBL6642183 | 0.67 | MAPT (0.45) | GAATDP1ALDH1A1KDM4EPOLB | |
| SCHEMBL6641965 | 0.66 | MAPT (0.42) | GAATDP1ALDH1A1KDM4EPOLB | |
| SCHEMBL29398039 | 0.65 | L3MBTL1 (0.63) | GAATDP1ALDH1A1KDM4EPOLB | |
| SCHEMBL9158223 | 0.65 | ALDH1A1 (0.55) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL7747088 | 0.64 | GAA (0.43) | GAATDP1ALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807105-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |