Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803576 | 0.83 | HTR4 (0.54) | HTR4ALDH1A1 | |
| SCHEMBL8803626 | 0.81 | GRM1 (0.42) | ACHEALDH1A1CHRNB4CHRNA3 | |
| SCHEMBL8803961 | 0.77 | SLC6A3 (0.48) | HTR4ACHEALDH1A1CASP6CRBN | |
| SCHEMBL8803953 | 0.77 | HTR4 (0.60) | HTR4ACHEALDH1A1CHRNB4CHRNA3 | |
| SCHEMBL7154189 | 0.72 | MEN1 (0.65) | HTR4ACHEALDH1A1 | |
| SCHEMBL10156660 | 0.71 | HPGD (0.67) | HTR4ACHEALDH1A1 | |
| SCHEMBL7278288 | 0.70 | HTR3E (0.56) | HTR4ALDH1A1CHRNB4CHRNA3 | |
| SCHEMBL7271032 | 0.70 | HTR3E (0.56) | HTR4ALDH1A1CHRNB4CHRNA3 | |
| SCHEMBL5925494 | 0.69 | GAA (0.64) | ALDH1A1CRBN | |
| SCHEMBL13880742 | 0.69 | CRBN (0.57) | HTR4ACHEALDH1A1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499995-B1 | Piperidine derivatives | NISSHIN FLOUR MILLING CO (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5246945-A | 5-hydroxytryptamine antagonist for nervous system disorders | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0499995-A2 | Piperidine derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-08-26 | — | — | EP | disclosed |