Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 7/20 | 0.41 |
| ▸ | HTR2B | P41595 | 6/20 | 0.40 |
| ▸ | HTR7 | P34969 | 5/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | RORB | Q92753 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441632 | 0.83 | BCAT2 (0.37) | BCAT2SLC9A1BAZ2BBAZ2APKM | |
| SCHEMBL8804547 | 0.80 | HTR2B (0.43) | SLC9A1HTR2BHTR7DRD2ADRA1D | |
| SCHEMBL1387943 | 0.79 | SLC9A1 (0.40) | SLC9A1HTR2BHTR7DRD2ADRA1D | |
| SCHEMBL8803075 | 0.78 | BCAT2 (0.43) | BCAT2BAZ2BBAZ2AMAPTPKM | |
| SCHEMBL8439989 | 0.77 | PKM (0.49) | LMNAMAPTPKMRORB | |
| SCHEMBL8803739 | 0.77 | SLC9A1 (0.52) | SLC9A1HTR2BHTR7 | |
| SCHEMBL7830859 | 0.76 | SLC9A1 (0.46) | SLC9A1 | |
| SCHEMBL8441628 | 0.74 | BCAT2 (0.39) | BCAT2BAZ2BBAZ2ARXFP1RORB | |
| Hydrochloric Acid SCHEMBL7827618 | 0.73 | HTR1A (0.48) | SLC9A1HTR2BHTR7DRD2ADRA1D | |
| Hydrochloric Acid SCHEMBL7828651 | 0.73 | HTR2B (0.55) | SLC9A1HTR2BHTR7DRD2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773927-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996004241-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |