SCHEMBL8804253

SCHEMBL8804253

CCOC(=O)NC(=S)CNc1ccc(C(=O)OC)c(S(=O)(=O)NC(=O)Nc2nc(OC)cc(OC)n2)c1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.51
GAA P10253 1/20 0.43
MAPT P10636 3/20 0.35
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
KMT2A Q03164 1/20 0.34
TP53 P04637 1/20 0.34
GLA P06280 1/20 0.34
ALOX12 P18054 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8782215 0.80 CDK1 (0.62) CDK1GAAMAPTKMT2ATP53
SCHEMBL8667253 0.80 ALDH1A1 (0.35) GAAMAPTKDM4EALDH1A1KMT2A
SCHEMBL8802884 0.78 CA2 (0.42) GAAMAPTKDM4EKMT2A
SCHEMBL5846414 0.78 CDK1 (0.62) CDK1GAAMAPTKDM4EALDH1A1
SCHEMBL10396053 0.78 CDK1 (0.62) CDK1GAAMAPTKMT2ATP53
SCHEMBL8535615 0.78 CDK1 (0.74) CDK1GAAMAPTKDM4EALDH1A1
SCHEMBL7458052 0.78 CDK1 (0.52) CDK1GAAMAPTKMT2ATP53
SCHEMBL6912875 0.78 CDK1 (0.73) CDK1GAAMAPTALDH1A1KMT2A
SCHEMBL5847785 0.78 CDK1 (0.61) CDK1GAAMAPTKDM4EALDH1A1
SCHEMBL5847781 0.78 CDK1 (0.61) CDK1GAAMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0666852-B1 NEW PHENYLSULPHONYL UREAS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1997-01-22 EP disclosed
US-5449812-A Substituted benzenesulfonamide derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1995-09-12 US disclosed
EP-0666852-A1 NEW PHENYLSULPHONYL UREAS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS. HOECHST SCHERING AGREVO GMBH (DE) 1995-08-16 EP disclosed
US-5401708-A Water soluble graft copolymer of unsaturated acid and a polysiloxane as a water resistant coating for thermal printing KANZAKI PAPER MFG. CO., LTD. (JP) 1995-03-28 US disclosed
WO-1994010154-A1 NEW PHENYLSULPHONYL UREAS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1994-05-11 WO disclosed
EP-0349194-B1 Heat-sensitive record material KANZAKI PAPER MFG CO LTD (JP) 1994-01-05 EP disclosed
EP-0308978-B1 MULTI-COLOR HEAT SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1993-04-07 EP disclosed
US-4977132-A CONTAINING FLUORAN DERIVATIVE, PHTHALIDE DERIVATIVE, PHENOLIC COMPOUND; STORAGE STABILITY KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-12-11 US disclosed
EP-0179492-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1990-05-02 EP disclosed
US-4910184-A Multilayer; containing pigment and polymer having glass KANZAKI PAPER MANUFACTURING COMPANY, LTD. (JP) 1990-03-20 US disclosed
US-4906604-A Multi-color heat sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-03-06 US disclosed
EP-0349194-A2 Heat-sensitive record material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-01-03 EP disclosed
EP-0308978-A2 Multi-color heat sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1989-03-29 EP disclosed
US-4626877-A RESIN LAYER CONTAINS A CATIONIC STARCH KANZAKI PAPER MANUFACTURING COMPANY, LIMITED (JP) 1986-12-02 US disclosed