Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CCKBR | P32239 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5530790 | 0.81 | NPC1 (0.43) | KMT2AMEN1SLC6A2SLC6A3GAA | |
| SCHEMBL8806674 | 0.78 | GAA (0.64) | KMT2AMEN1KDM4EHSD17B10GAA | |
| SCHEMBL8804263 | 0.75 | CYP3A4 (0.52) | KMT2AMEN1KDM4ECCKBRSMN1; SMN2 | |
| SCHEMBL8805163 | 0.74 | EGFR (0.53) | KMT2AMEN1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL8805923 | 0.74 | ROCK2 (0.45) | KMT2AMEN1GAASMN1; SMN2NPC1 | |
| SCHEMBL8805727 | 0.74 | RAB9A (0.57) | KMT2AMEN1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL8804981 | 0.73 | ROCK2 (0.54) | KMT2AMEN1KDM4EHSD17B10CCKBR | |
| SCHEMBL8805800 | 0.73 | ALDH1A1 (0.50) | KMT2AMEN1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL8805578 | 0.72 | ALDH1A1 (0.51) | KMT2AMEN1CCKBRSMN1; SMN2CYP1A2 | |
| SCHEMBL8805183 | 0.72 | CYP3A4 (0.49) | KMT2AMEN1KDM4ECCKBRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775131-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA Medica Aktiengesellschaft (DE) | 1997-05-28 | — | — | EP | disclosed |