Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19321713 | 0.88 | CYP1A2 (0.45) | MEN1KMT2ACYP1A2CYP2A6TAAR1 | |
| SCHEMBL8804326 | 0.88 | CYP1A2 (0.45) | MEN1KMT2ACYP1A2CYP2A6TAAR1 | |
| SCHEMBL8803735 | 0.85 | MEN1 (0.47) | MEN1KMT2ATAAR1ALDH1A1THRA | |
| SCHEMBL8802944 | 0.81 | MEN1 (0.47) | MEN1KMT2ATAAR1 | |
| SCHEMBL8804058 | 0.81 | KMT2A (0.47) | MEN1KMT2AHRH1CYP1A2TAAR1 | |
| SCHEMBL19347555 | 0.81 | ALOX5 (0.51) | MEN1KMT2ATAAR1IGF1RALOX15 | |
| SCHEMBL8803380 | 0.80 | CALM1 (0.51) | MEN1KMT2ATAAR1IGF1RALOX15 | |
| SCHEMBL51024 | 0.80 | MEN1 (0.69) | MEN1KMT2ATAAR1 | |
| SCHEMBL8802834 | 0.78 | MEN1 (0.45) | MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL8803757 | 0.77 | TAAR1 (0.47) | MEN1KMT2ATAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492474-B1 | 1,3-Dioxolane derivatives as cholesterol-lowering agents | SYNTEX INC (US) | 1997-03-05 | — | — | EP | disclosed |
| US-5158949-A | 1,3-DIOXOLANE DERIVATIVES AS CHOLESTEROL-LOWERING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1992-10-27 | — | — | US | disclosed |
| EP-0492474-A1 | 1,3-Dioxolane derivatives as cholesterol-lowering agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-01 | — | — | EP | disclosed |