SCHEMBL880478

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13522300	0.92	ALDH1A1 (0.88)	ALDH1A1KDM4EMAPTMEN1KMT2A
	SCHEMBL880412	0.90	ALDH1A1 (0.84)	ALDH1A1KDM4EMAPTMEN1KMT2A
	SCHEMBL880481	0.88	KDM4E (0.81)	ALDH1A1KDM4EMAPTMEN1KMT2A
	SCHEMBL880413	0.83	ALDH1A1 (0.77)	ALDH1A1KDM4EMAPTMEN1KMT2A
	SCHEMBL10280642	0.81	ALDH1A1 (0.70)	ALDH1A1KDM4EMAPTMEN1KMT2A
	SCHEMBL880480	0.80	MAPT (1.00)	ALDH1A1KDM4EMAPTMEN1KMT2A
	SCHEMBL880258	0.79	NPSR1 (0.92)	ALDH1A1KDM4EMAPTMEN1KMT2A
	SCHEMBL29004406	0.78	KDM4E (0.69)	ALDH1A1KDM4EMAPTMEN1KMT2A
	SCHEMBL20672996	0.78	ADCY1 (1.00)	ADCY8ADCY1
	SCHEMBL20657977	0.78	ADCY1 (0.72)	ALDH1A1KDM4EMEN1KMT2AADCY8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.